Key Publications
Degrons: unraveling the lexicon of the ubiquitin-proteasome system
Zhang Z, Mena EL, Timms RT, Koren I, Elledge S
Nat Rev Mol Cell Biol (2025)
Defining E3 ligase-substrate relationships through multiplex CRISPR screening
Timms RT*, Mena EL*, Leng Y, Li MZ, Tchasovnikarova IA, Koren I, Elledge SJ
Nature Cell Biol (2023)
Structural basis and regulation of the reductive stress response
Manford AG*, Mena EL*, Shih KY, Gee CL, McMinimy R, Martínez-González B, Sherriff R, Lew B, Zoltek M, Rodríguez-Pérez F, Woldesenbet M, Kuriyan J, Rape M
Cell (2021)
ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection
Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, Ueberheide B, Gygi SP, Pagano M, Harper JW, Davey RA, Elledge SJ
Proc Natl Acad Sci U S A (2021)
Structural basis for dimerization quality control
Mena EL, Jevtić P, Greber BJ, Gee CL, Lew BG, Akopian D, Nogales E, Kuriyan J, Rape M
Nature (2020)
Dimerization quality control ensures neuronal development and survival
Mena EL, Kjolby RAS, Saxton RA, Werner A, Lew BG, Boyle JM, Harland R, Rape M
Science (2018)
* co-first author
A complete publication list can be found on Pubmed.